The Future of Quark Matter at RHIC

Projected annual results for heavy particle and high-p_{T} correlation studies at future RHICII luminosities.Comment: 8 pages, 3 figures. Proceedings for Quark Matter 2006, Shanghai, Chin

Impact of phenylpropanoid compounds on heat stress tolerance in carrot cell cultures

The phenylpropanoid and flavonoid families include thousands of specialized metabolites that influence a wide range of processes in plants, including seed dispersal, auxin transport, photoprotection, mechanical support and protection against insect herbivory. Such metabolites play a key role in the protection of plants against abiotic stress, in many cases through their well-known ability to inhibit the formation of reactive oxygen species (ROS). However, the precise role of specific phenylpropanoid and flavonoid molecules is unclear. We therefore investigated the role of specific anthocyanins (ACs) and other phenylpropanoids that accumulate in carrot cells cultivated in vitro, focusing on their supposed ability to protect cells from heat stress. First we characterized the effects of heat stress to identify quantifiable morphological traits as markers of heat stress susceptibility. We then fed the cultures with precursors to induce the targeted accumulation of specific compounds, and compared the impact of heat stress in these cultures and unfed controls. Data modeling based on Projection to Latent Structures (PLS) regression revealed that metabolites containing coumaric or caffeic acid, including ACs, correlate with less heat damage. Further experiments suggested that one of the cellular targets damaged by heat stress and protected by these metabolites is the actin microfilament cytoskeleton

Equilibrium solvation in quadrupolar solvents

We present a microscopic theory of equilibrium solvation in solvents with zero dipole moment and non-zero quadrupole moment (quadrupolar solvents). The theory is formulated in terms of autocorrelation functions of the quadrupolar polarization (structure factors). It can be therefore applied to an arbitrary dense quadrupolar solvent for which the structure factors are defined. We formulate a simple analytical perturbation treatment for the structure factors. The solute is described by coordinates, radii, and partial charges of constituent atoms. The theory is tested on Monte Carlo simulations of solvation in model quadrupolar solvents. It is also applied to the calculation of the activation barrier of electron transfer reactions in a cleft-shaped donor-acceptor complex dissolved in benzene with the structure factors of quadrupolar polarization obtained from Molecular Dynamics simulations.Comment: Submitted to J. Chem. Phys., 20 pages and 13 figure

Climbing the water ladder: multiple-use water services for poverty reduction

Multiple use / Models / Water productivity / Research projects / Water supply / Domestic water / Irrigation water / Water governance / Poverty / Gender / Rural areas / Wells / Water harvesting / Runoff / Water storage / Water purification / Appropriate technology / Costs / Local government / Non governmental organizations / Case studies / Ehiopia / Nepal / Zimbabwe / Bolivia / India / Colombia / Thailand / South Africa

Sivers and Boer-Mulders functions in Light-Cone Quark Models

Results for the naive-time-reversal-odd quark distributions in a light-cone quark model are presented. The final-state interaction effects are generated via single-gluon exchange mechanism. The formalism of light-cone wave functions is used to derive general expressions in terms of overlap of wave-function amplitudes describing the different orbital angular momentum components of the nucleon. In particular, the model predictions show a dominant contribution from S- and P-wave interference in the Sivers function and a significant contribution also from the interference of P and D waves in the Boer-Mulders function. The favourable comparison with existing phenomenological parametrizations motivates further applications to describe azimuthal asymmetries in hadronic reactions.Comment: references and explanations added; version to appear in Phys. Rev.

Blue Straggler Stars: The Spectacular Population in M80

Using HST-WFPC2 observations in two ultraviolet (UV) filters (F225W and F336W) of the central region of the high density Galactic Globular cluster (GGC) M80 we have identified 305 Blue Straggler Stars (BSS) which represents the largest and most concentrated population of BSS ever observed in a GGC. We also identify the largest, clean sample of evolved BSS yet found. The high stellar density alone cannot explain the BSS, and we suggest that in M80 we are witnessing a transient dynamical state, during which stellar interactions are delaying the core-collapse process leading to an exceptionally large population of collisional-BSS.Comment: 15 pages, 5 figures, Astrophysical Journal Letters, in pres

Emulating opportunistic networks with KauNet Triggers

In opportunistic networks the availability of an end-to-end path is no longer required. Instead opportunistic networks may take advantage of temporary connectivity opportunities. Opportunistic networks present a demanding environment for network emulation as the traditional emulation setup, where application/transport endpoints only send and receive packets from the network following a black box approach, is no longer applicable. Opportunistic networking protocols and applications additionally need to react to the dynamics of the underlying network beyond what is conveyed through the exchange of packets. In order to support IP-level emulation evaluations of applications and protocols that react to lower layer events, we have proposed the use of emulation triggers. Emulation triggers can emulate arbitrary cross-layer feedback and can be synchronized with other emulation effects. After introducing the design and implementation of triggers in the KauNet emulator, we describe the integration of triggers with the DTN2 reference implementation and illustrate how the functionality can be used to emulate a classical DTN data-mule scenario

Temporal and causal reasoning in deaf and hearing novice readers

Temporal and causal information in text are crucial in helping the reader form a coherent representation of a narrative. Deaf novice readers are generally poor at processing linguistic markers of causal/temporal information (i.e., connectives), but what is unclear is whether this is indicative of a more general deficit in reasoning about temporal/causal information. In Study 1, 10 deaf and 63 hearing children, matched for comprehension ability and age, were compared on a range of tasks tapping temporal/causal reasoning skills. In Study 2, 20 deaf and 32 hearing children, matched for age but not reading comprehension ability, were compared on revised versions of the tasks. The pattern of performance of the deaf was different from that of the hearing; they had difficulties when temporal and causal reasoning was text-based, but not when it was nonverbal, indicating that their global temporal/causal reasoning skills are comparable with those of their hearing counterparts

Wnt5a induces ROR1 to recruit cortactin to promote breast-cancer migration and metastasis.

ROR1 is a conserved oncoembryonic surface protein expressed in breast cancer. Here we report that ROR1 associates with cortactin in primary breast-cancer cells or in MCF7 transfected to express ROR1. Wnt5a also induced ROR1-dependent tyrosine phosphorylation of cortactin (Y421), which recruited ARHGEF1 to activate RhoA and promote breast-cancer-cell migration; such effects could be inhibited by cirmtuzumab, a humanized mAb specific for ROR1. Furthermore, treatment of mice bearing breast-cancer xenograft with cirmtuzumab inhibited cortactin phosphorylation in vivo and impaired metastatic development. We established that the proline at 841 of ROR1 was required for it to recruit cortactin and ARHGEF1, activate RhoA, and enhance breast-cancer-cell migration in vitro or development of metastases in vivo. Collectively, these studies demonstrate that the interaction of ROR1 with cortactin plays an important role in breast-cancer-cell migration and metastasis